Comments for John Simm Society Blog http://blog.johnsimmsociety.com Mon, 31 Oct 2011 16:39:10 +0000 hourly 1 http://wordpress.com/ Comment on The Horror of Hamlet – John Simm by Heather http://blog.johnsimmsociety.com/2011/10/30/the-horror-of-hamlet-john-simm/#comment-623 Mon, 31 Oct 2011 16:39:10 +0000 http://blog.johnsimmsociety.com/?p=2938#comment-623 I wonder if Sir Ian McKellen was thinking, he was staring at the master (and Sam Tyler)…..(for me, it would be Magneto too….together with good old Gandalf the white)

]]> Comment on RTS North West Nominations – Best Performance in a Single Drama: John Simm for Exile by Heather http://blog.johnsimmsociety.com/2011/09/28/rts-north-west-nominations-best-performance-in-a-single-drama-john-simm-for-exile/#comment-614 Thu, 06 Oct 2011 09:57:20 +0000 http://blog.johnsimmsociety.com/?p=2889#comment-614 I absolut agree and wish Mister Simm the award!
This scene was heartbreaking…..

]]> Comment on RTS North West Nominations – Best Performance in a Single Drama: John Simm for Exile by Elaine http://blog.johnsimmsociety.com/2011/09/28/rts-north-west-nominations-best-performance-in-a-single-drama-john-simm-for-exile/#comment-607 Fri, 30 Sep 2011 21:27:57 +0000 http://blog.johnsimmsociety.com/?p=2889#comment-607 John Simm deserves to win shed-loads of awards for ‘Exile’ – the scene where his character (Tom Ronstadt) watches that video message on his laptop was the single, most moving moment in television this year. Unless you count the penultimate scene (Simm and Broadbent in the nursing home)… fabulous. Everyone I have shown this to has loved it.

]]> Comment on Bafta television awards 2011: Small-screen stars in pictures by Bafta television awards 2011: Small-screen stars in pictures … | Top Celebrity http://blog.johnsimmsociety.com/2011/05/20/bafta-television-awards-2011-small-screen-stars-in-pictures/#comment-576 Sat, 21 May 2011 06:56:01 +0000 http://blog.johnsimmsociety.com/?p=2545#comment-576 [...] Read more here: Bafta television awards 2011: Small-screen stars in pictures … [...]

]]> Comment on John Simm, career profile by Heather http://blog.johnsimmsociety.com/2011/05/06/john-simm-career-profile/#comment-541 Mon, 09 May 2011 16:53:37 +0000 http://blog.johnsimmsociety.com/?p=2479#comment-541 The telegraph forgot Mister Simm`s role as Sam Tyler in “Life on Mars” (as to be seen on the original side), he was nominated Bafta for best actor. I can`t believe it.
Simm also was the star in BBC drama “Never , Never”…2000….and in the stunning movie “Forgive and Forget”
2007…he has given “Elling” in theatre, for which he was nominated for the Laurence Olivier Award!
Not to forget that he returned as Master 2009…

]]> Comment on BBC Press Office – Exile Programme Information by Barry Henley http://blog.johnsimmsociety.com/2011/04/14/bbc-press-office-exile-programme-information/#comment-539 Sun, 08 May 2011 12:29:34 +0000 http://blog.johnsimmsociety.com/?p=2194#comment-539 Exellent production and gripping to the end. Whole family are fans of John Simms and can’t wait to see him in his next acting role.

]]> Comment on Exile: New BBC One dramas to depict corruption and conspiracy of UK politics by Julian Lieb,M.D http://blog.johnsimmsociety.com/2011/04/03/exile-new-bbc-one-dramas-to-depict-corruption-and-conspiracy-of-uk-politics/#comment-519 Sat, 30 Apr 2011 09:59:17 +0000 http://blog.johnsimmsociety.com/?p=1756#comment-519 .
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THE REMARKABLE HUMAN AND ECONOMIC VALUE OF ANTIDEPRESSANTS IN PREVENTING AND ALLEVIATING ALZHEIMER’S DISEASE
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Improving depression and enhancing resilience in family dementia caregivers: a pilot randomized placebo-controlled trial of escitalopram.
Lavretsky H, Siddarth P, Irwin MR. Am J Geriatr Psychiatry. 2010 Feb; 18(2):154-62.PMID: 20104071 [PubMed - indexed for MEDLINE
Anti-inflammatory effects of antidepressants: possibilities for preventives against Alzheimer's disease. Hashioka S, McGeer PL, Monji A, Kanba S.
Cent Nerv Syst Agents Med Chem. 2009 Mar; 9(1):12-9. Review.PMID: 20021334 [PubMed - indexed for MEDLINE]
Imipramine, in part through tumor necrosis factor alpha inhibition, prevents cognitive decline and beta-amyloid accumulation in a mouse model of Alzheimer’s disease.
Chavant F, Deguil J, Pain S, Ingrand I, Milin S, Fauconneau B, Pérault-Pochat MC, Lafay-Chebassier C. J Pharmacol Exp Ther. 2010 Feb; 332(2):505-14. Epub 2009 Nov 4.
Involuntary emotional expression disorder in Alzheimer’s disease – psychopharmacotherapy aspects. Mimica N, Drmić S, Presecki P. Psychiatr Danub. 2009 Sep; 21(3):425-8.
Untangling the roles of antidepressants and mood stabilizers in the treatment of Alzheimer’s disease. Introduction. Reiman EM. J Clin Psychiatry. 2009 Jun;70(6):913-4. No abstract available.
Effect of a serotonin reuptake inhibitor on irritability, apathy, and psychotic symptoms in patients with Alzheimer’s disease. Siddique H, Hynan LS, Weiner MF. J Clin Psychiatry. 2009 Jun; 70(6):915-8. Epub 2009 May 5.
Antidepressants and dementia. Kessing LV, Søndergård L, Forman JL, Andersen PK.
J Affect Disord. 2009 Sep; 117(1-2):24-9. Epub 2009 Jan 12.
Int Rev Psychiatry. 2008 Aug; 20(4):382-8.
Depression in Alzheimer’s disease: phenomenology, clinical correlates and treatment.
Effect of citalopram in treating hypersexuality in an Alzheimer’s disease case.
Tosto G, Talarico G, Lenzi GL, Bruno G. Neurol Sci. 2008 Sep; 29(4):269-70. Epub 2008 Sep 20
Dement Geriatr Cogn Disord. 2008; 25(4):372-9. Epub 2008 Mar 20. Is antidepressant treatment associated with reduced cognitive decline in Alzheimer’s disease? Mossello E, Boncinelli M, Caleri V, Cavallini MC, Palermo E, Di Bari M, Tilli S, Sarcone E, Simoni D, Biagini CA, Masotti G, Marchionni N. Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy. enrico.mossello@unifi.it J Biol Chem. 2007 Nov 9; 282(45):32676-88. Epub 2007 Sep 2.
Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo. Hoshino T, Nakaya T, Homan T, Tanaka K, Sugimoto Y, Araki W, Narita M, Narumiya S, Suzuki T, Mizushima T.Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan. J Biol chem. 2007 Nov 9; 282(45):32676-88. Epub 2007 Sep 2.
,
.For emphasis:
Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial. Chollet F, Tardy J, Albucher JF, Thalamas C, Berard E, Lamy C, Bejot Y, Deltour S, Jaillard A, Niclot P, Guillon B, Moulin T, Marque P, Pariente J, Arnaud C, Loubinoux I. Lancet Neurol. 2011 Feb; 10(2):123-30. Epub 2011 Jan 7. Erratum in: Lancet Neurol. 2011 Mar; 10(3):205. PMID: 21216670 [PubMed - indexed for MEDLINE]

BIOCHEMICAL AND PHARMACOLOGICAL INTERPRETATIONS

As depression predisposes to Alzheimer’s disease,, it is reasonable to suspect that antidepressants are capable of preventing, alleviating and arresting the disorder. Excessive synthesis of prostaglandin E2 generates amyloid. Such non-steroidal anti-inflammatory drugs as aspirin and ibuprofen, as well as antidepressants, inhibit prostaglandin E2. Two major epidemical studies have shown that ibuprofen (Motrin) that specifically inhibits prostaglandins, can significantly delay the onset of Parkinson’s disease, a neurodegenerative disorder closely related to Alzheimer’s.

Antidepressants offer great advantages, and few disadvantages, in addressing Alzheimer’s, and beggars can’t be choosers Alzheimer’s was recently referred to as “the coming tsunami,” but you would not think so, given the lack of enthusiasm of Alzheimer’s organizations and health policy makers, when notified of this resource.

The right to the highest attainable standard of health is codified in numerous legally binding international and regional human rights treaties. The right, or other health-related rights, is also enshrined in over 100 constitutions worldwide.
Many additional refs.in Pubmed.

For educational purposes only.

]]> Comment on John Simm Promotional Tour for Exile by Heather http://blog.johnsimmsociety.com/2011/04/29/john-simm-promotional-tour-for-exile/#comment-518 Sat, 30 Apr 2011 09:21:17 +0000 http://blog.johnsimmsociety.com/?p=2413#comment-518 Great…big thanks for putting all that together!

And again…join us please with the petition for bringing the Master back as Mister John Simm!

http://www.ipetitions.com/petition/johnsimmasmaster/

]]> Comment on ‘Doctor Who’ exec: ‘John Simm could return’ by Heather http://blog.johnsimmsociety.com/2011/04/15/doctor-who-exec-john-simm-could-return/#comment-510 Thu, 28 Apr 2011 16:20:17 +0000 http://blog.johnsimmsociety.com/?p=2207#comment-510 A little petition may help the Master….
vote, well….join if you like, please!

http://www.ipetitions.com/petition/johnsimmasmaster/

]]> Comment on John Simm: ‘I wish I’d done another series of Life on Mars’ by Heather http://blog.johnsimmsociety.com/2011/04/21/john-simm-i-wish-id-done-another-series-of-life-on-mars/#comment-489 Sat, 23 Apr 2011 10:12:17 +0000 http://blog.johnsimmsociety.com/?p=2376#comment-489 May be this could help….
http://www.ipetitions.com/petition/johnsimmasmaster/

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